1. Buy EZ Pass (or local equivalent). Constantly amazed how many people don't have it. Takes one online visit and removes waiting in the toll lines and trying to hunt down money at each stop. State after state, so many people without EZ Pass waiting in those lines.
2. Try the alarm clock feature on the BlackBerry or cell phone. Easy to set up, works great. Wake-up calls and in-room alarm clocks just aren't always reliable.